2026-06-26
Is your siRNA "silent" again? No, silence is useless! A must-read guide for researchers to avoid the pitfalls of oligonucleic acid testing!
For small nucleic acid tools such as siRNA and shRNA, this guide covers best practices to avoid common pitfalls across the entire workflow – from sequence design and chemical modification to transfection experiments – including target selection, off‑target control, proper controls, and in vivo delivery strategies. GentleGen's one‑stop service platform deeply integrates core capabilities including target evaluation, sequence design, synthesis and purification, activity screening, and modification conjugation, delivering an "idea‑to‑reality" R&D experience for nucleic acid drug development.